Serum concentration of 25(OH)D in children with recurrent infections from Łódź Province
Vitamin D plays an important role in regulation of innate and acquired immunity. The aim of the study was to assess the serum concentration of a vitamin D metabolite – 25(OH)D – in children with recurrent respiratory tract infections. Two hundred and ninety-six children with recurrent infections,...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Medical Communications Sp. z o.o.
2018-06-01
|
| Series: | Pediatria i Medycyna Rodzinna |
| Subjects: | |
| Online Access: | http://www.pimr.pl/index.php/issues/2018-vol-14-no-2/serum-concentration-of-25-oh-d-in-children-with-recurrent-infections-from-lodz-province?aid=1194 |
| Summary: | Vitamin D plays an important role in regulation of innate and acquired immunity. The aim of the study was to assess the
serum concentration of a vitamin D metabolite – 25(OH)D – in children with recurrent respiratory tract infections.
Two hundred and ninety-six children with recurrent infections, aged 1–18 years, who were hospitalised in the Department
of Paediatrics and Allergy for an extended diagnosis of recurrent infections were recruited. The hepatic metabolite
of vitamin D, namely 25(OH)D was determined in the analysed sera in different seasons of the year. Sixty-one per cent
of the children had a low concentration of 25(OH)D. The vitamin D level was shown to be inversely correlated with the age
of the patient; the younger the child, the higher the serum concentration of calcidiol. There was no correlation between the
concentration of 25(OH)D and gender or season of the year in which the measurements were done. The results showed
that vitamin D deficiency (serum concentration below 30 ng/mL) is common in children with recurrent respiratory tract
infections from the region of Łódź. |
|---|---|
| ISSN: | 1734-1531 2451-0742 |