Chronic constipation as a risk factor of urinary tract infection in children

• Main Author: Irna Fajri Syahny Mohammad Juffrie Pungky Ardany Kusuma
• Format: Article
• Language: English
• Published: Universitas Gadjah Mada 2014-08-01
• Series: Journal of the Medical Sciences
• Online Access: https://jurnal.ugm.ac.id/bik/article/view/5033

The prevalence of urinary tract infection (UTI) in children is still quite high. In Dr. Sardjito General Hospital, Yogyakarta the incidence of UTI is reported about 3.5%. One of the risk factors of the incidence of UTI is chronic constipation. However, it is often not a concern in the management of UTI pediatric patients. The aim of the study was to evaluate the influence of chronic constipation in increasing the risk of UTI in children. This was an observational study with case-control design. Children with symptoms of UTI who visited at the Installation of Child Health, Dr. Sardjito General Hospital, Yogyakarta underwent dipstick urinalysis test and urine culture examination. Patients who showed positive urine culture was included in the case group, meanwhile patients who showed negative urine culture was included in the control group. All patients were then asked the history of the chronic constipation. The association between the constipation and the incident of UTI was evaluated using bivariate analysis continued by multivariate analysis. One hundred and twenty eight eligible subjects consisting 64 subjects in each group were involved in this study. Statistical analysis showed that children with chronic constipation have a 3.77 times higher risk of UTI (OR=3.77; 95%CI=3.21-4.32) compare to those without constipation. Furthermore, the chronic constipation remained to be independent risk factor of UTI. The incidence of UTI increased 3.99 times higher in children with constipation compare to those without constipation (aOR=3.99; 95% CI=1.028-15.48). In conclusion, chronic constipation has been proven to be a risk factor of UTI in children