Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice

Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice

ABSTRACT The most recently identified serotonin (5-HT) receptor is the 5-HT7 receptor. The antinociceptive effects of a 5-HT7 receptor agonist have been shown in neuropathic and inflammatory animal models of pain. A recent study demonstrated the functional expression of 5-HT7 receptors in the substa...

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Bibliographic Details
Main Authors: Kadriye DEMİRKAYA, Özlem Martı AKGÜN, Buğra ŞENEL, Zeynep ÖNCEL TORUN, Melik SEYREK, Enza LACİVİTA, Marcello LEOPOLDO, Ahmet DOĞRUL
Format: Article
Language:English
Published: University of São Paulo
Series:Journal of Applied Oral Science
Subjects:
Formalin
Receptor agonists
Orofacial pain
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572016000300218&lng=en&tlng=en

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