Microwave Assisted Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing the 1,2,3-Thiadiazole Moiety

Microwave Assisted Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing the 1,2,3-Thiadiazole Moiety

In order to investigate the biological activity of 1,2,4-triazole compounds, seventeen novel 1,2,4-triazole derivatives containing 1,2,3-thiadiazole moieties were synthesized by multi-step reactions under microwave assisted conditions. The structures were characterized by 1H-NMR, 13C-NMR, MS and ele...

Full description

Bibliographic Details
Main Authors:	Cheng-Xia Tan, Xing-Hai Liu, Jian-Zhong Jin, Jian-Quan Weng, Jian-Qun Fu, Na-Bo Sun
Format:	Article
Language:	English
Published:	MDPI AG 2013-10-01
Series:	Molecules
Subjects:	1,2,4-triazole 1,2,3-thiadiazole synthesis fungicidal activity thioether theoretical calculations
Online Access:	http://www.mdpi.com/1420-3049/18/10/12725

Similar Items

Microwave Assistant Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing Pyridine Moiety
by: Guo-Xiang Sun, et al.
Published: (2014-05-01)

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety
by: Nadia A. Abdelriheem, et al.
Published: (2017-02-01)

Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety
by: Li-Jing Min, et al.
Published: (2015-11-01)

Synthesis and Biological Properties of Novel Triazole-Thiol and Thiadiazole Derivatives of the 1,2,4-Triazole-3(5)-one Class
by: Esra Düğdü, et al.
Published: (2014-02-01)

Dataset on theoretical bio-evaluation of 1,2,4-thiadiazole-1,2,4-triazole analogues against epidermal growth factor receptor kinase down regulating human lung cancer
by: Abel Kolawole Oyebamiji, et al.
Published: (2021-08-01)

Synthesis of Some Substituted 1,3,4-Oxadiazoles, Thiadiazoles and 1,2,4-Triazoles from Acid Chlorides
by: E. Q. Mahmood, et al.
Published: (2013-06-01)

Synthesis and Cytotoxicity Evaluation of Some Novel Thiazoles, Thiadiazoles, and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones Incorporating Triazole Moiety
by: Sobhi M. Gomha, et al.
Published: (2015-01-01)

Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation
by: Rezki Nadjet, et al.
Published: (2017-09-01)

Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff bases incorporating imidazole moiety as potential antimicrobial agents
by: Aouad Mohamed Reda, et al.
Published: (2015-06-01)

Synthesis and Antifungal Activity of Novel Myrtenal-Based 4-Methyl-1,2,4-triazole-thioethers
by: Gui-Shan Lin, et al.
Published: (2017-01-01)

Synthesis and Biological Activities of Ethyl 2-(2-pyridylacetate) Derivatives Containing Thiourea, 1,2,4-triazole, Thiadiazole and Oxadiazole Moieties
by: Daniel Szulczyk, et al.
Published: (2017-03-01)

Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether
by: Mohamed Reda Aouad, et al.
Published: (2017-11-01)

Synthesis of Biologically Relevant 1,2,3- and 1,3,4-Triazoles: From Classical Pathway to Green Chemistry
by: Lori Gonnet, et al.
Published: (2021-09-01)

Synthesis of some substituted 1,3,4-oxadiazoles, thiadiazoles and 1,2,4-triazoles
by: Shereen R. Mohamed
Published: (2009-06-01)

Multi-Armed 1,2,3-Selenadiazole and 1,2,3-Thiadiazole Benzene Derivatives as Novel Glyoxalase-I Inhibitors
by: Qosay A. Al-Balas, et al.
Published: (2019-09-01)

Design, Synthesis and Fungicidal Activity of New 1,2,4-Triazole Derivatives Containing Oxime Ether and Phenoxyl Pyridinyl Moiety
by: Hui Bai, et al.
Published: (2020-12-01)

Synthesis and Antifungal Activity of Benzamidine Derivatives Carrying 1,2,3-Triazole Moieties
by: Guangyou Chen, et al.
Published: (2014-05-01)

Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents
by: Nadjet Rezki, et al.
Published: (2015-09-01)

Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety
by: Cristian Peptu, et al.
Published: (2009-07-01)

Synthesis, Structural Studies and Biological Evaluation of Connections of Thiosemicarbazide, 1,2,4-Triazole and 1,3,4-Thiadiazole with Palmitic Acid
by: Michał Jóźwiak, et al.
Published: (2018-04-01)

Synthesis of new, highly luminescent bis(2,2’-bithiophen-5-yl) substituted 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole
by: Anastasia S. Kostyuchenko, et al.
Published: (2014-07-01)

Synthesis of Novel Glycerol-Derived 1,2,3-Triazoles and Evaluation of Their Fungicide, Phytotoxic and Cytotoxic Activities
by: Adilson Vidal Costa, et al.
Published: (2017-10-01)

Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole <i>N</i>-glycosides
by: Fahad M. Alminderej, et al.
Published: (2019-10-01)

Synthesis of some new pyrazolo[1,5-a]pyrimidine, pyrazolo[5,1-c]triazine, 1,3,4-thiadiazole and pyridine derivatives containing 1,2,3-triazole moiety
by: Nadia A. Abdelriheem, et al.
Published: (2017-06-01)

I2/DMSO-Catalyzed Transformation of N-tosylhydrazones to 1,2,3-thiadiazoles
by: Weiwei Li, et al.
Published: (2020-06-01)

Synthesis and Biological Activity of Substituted Urea and Thiourea Derivatives Containing 1,2,4-Triazole Moieties
by: David E. Wedge, et al.
Published: (2013-03-01)

Synthesis Some of New Substituted 1,3,4-Thiadiazole and 1,2,4-Triazole
by: Tamara alsafar, et al.
Published: (2020-03-01)

Synthesis and antibacterial activity of 1-N-(β-d-glucopyranosyl)-4-((1-substituted-1H-1,2,3-triazol-4-yl)ethoxymethyl)-1,2,3-triazoles
by: Adnan Ibrahim Mohammed, et al.
Published: (2017-05-01)

Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Having a D,L-Methionine Moiety
by: Aurel Pui, et al.
Published: (2007-01-01)

Synthesis of aryl-1H-1,2,3-triazoles via 1,3-dipolar cycloaddition
by: Wagner O. Valença, et al.
Published: (2012-06-01)

New Thiosemicarbazides and 1,2,4-Triazolethiones Derived from 2-(Ethylsulfanyl) Benzohydrazide as Potent Antioxidants
by: Nafal Nazarbahjat, et al.
Published: (2014-08-01)

5-Amino-3-methyl-1,2,4-thiadiazole
by: R. Alan Aitken, et al.
Published: (2018-01-01)

5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles
by: Robby Vroemans, et al.
Published: (2020-04-01)

New S-alkylated 1,2,4-triazoles incorporating diphenyl sulfone moieties with potential antibacterial activity
by: Barbuceanu Stefania F., et al.
Published: (2009-01-01)

5-Methyl-N′-(5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbonyl)-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide
by: Gamal A. El-Hiti, et al.
Published: (2018-03-01)

Synthesis of new 1H-1,2,3-triazole-1,4-naphthoquinones
by: Wagner O. Valença, et al.
Published: (2012-06-01)

Strategies Towards the Synthesis of N2-Substituted 1,2,3-Triazoles
by: RODRIGO OCTÁVIO M.A. DE SOUZA, et al.
Published: (2019-02-01)

4-(7-Bromobenzo[<i>d</i>][1,2,3]thiadiazol-4-yl)morpholine
by: Nikita S. Gudim, et al.
Published: (2021-04-01)

Triazole-Modified Peptidomimetics: An Opportunity for Drug Discovery and Development
by: Agnieszka Staśkiewicz, et al.
Published: (2021-05-01)

Synthetic Transformations and Medicinal Significance of 1,2,3-Thiadiazoles Derivatives: An Update
by: Ali Irfan, et al.
Published: (2021-06-01)