Treatment with high-dose simvastatin reduces secretion of apolipoprotein B-lipoproteins in patients with diabetic dyslipidemia
HMG-CoA reductase inhibitors (statins) are effective lipid-altering drugs for the treatment of dyslipidemia in patients with type 2 diabetes mellitus. We conducted a randomized, double-blind, placebo-controlled, crossover design trial to determine the effects of simvastatin, 80 mg/day, on plasma lip...
Main Authors: | Merle Myerson, Colleen Ngai, Jeffrey Jones, Steve Holleran, Rajasekhar Ramakrishnan, Lars Berglund, Henry N. Ginsberg |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-12-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520328625 |
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