The pig as a preclinical traumatic brain injury model: current models, functional outcome measures, and translational detection strategies

The pig as a preclinical traumatic brain injury model: current models, functional outcome measures, and translational detection strategies

Traumatic brain injury (TBI) is a major contributor of long-term disability and a leading cause of death worldwide. A series of secondary injury cascades can contribute to cell death, tissue loss, and ultimately to the development of functional impairments. However, there are currently no effective...

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Bibliographic Details
Main Authors: Holly A. Kinder, Emily W. Baker, Franklin D. West
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
traumatic brain injury; large animal model; pig model; diffuse axonal injury; functional outcome assessment measures; controlled cortical impact model; fluid percussion injury model; magnetic resonance imaging
biomarkers
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=3;spage=413;epage=424;aulast=Kinder

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