Label-free detection of neuronal differentiation in cell populations using high-throughput live-cell imaging of PC12 cells.

Detection of neuronal cell differentiation is essential to study cell fate decisions under various stimuli and/or environmental conditions. Many tools exist that quantify differentiation by neurite length measurements of single cells. However, quantification of differentiation in whole cell populati...

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Bibliographic Details
Main Authors: Sebastian Weber, María L Fernández-Cachón, Juliana M Nascimento, Steffen Knauer, Barbara Offermann, Robert F Murphy, Melanie Boerries, Hauke Busch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579923?pdf=render