Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence.

Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence.

Gene rearrangement occurs during development in some cell types and this genome dynamics is modulated by intrinsic and extrinsic factors, including growth stimulants and nutrients. This raises a possibility that such structural change in the genome and its subsequent epigenetic modifications may als...

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Bibliographic Details
Main Authors: Yih-Horng Shiao, Robert M Leighty, Cuiju Wang, Xin Ge, Erik B Crawford, Joshua M Spurrier, Sean D McCann, Janet R Fields, Laura Fornwald, Lisa Riffle, Craig Driver, Octavio A Quiñones, Ralph E Wilson, Kazimierz S Kasprzak, Gregory S Travlos, W Gregory Alvord, Lucy M Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3134480?pdf=render

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