Differential regulation of the CXCR2 chemokine network in rat brain trauma: Implications for neuroimmune interactions and neuronal survival

Chemokine receptors represent promising targets to attenuate inflammatory responses and subsequent secondary damage after brain injury. We studied the response of the chemokines CXCL1/CINC-1 and CXCL2/MIP-2 and their receptors CXCR1 and CXCR2 after controlled cortical impact injury in adult rats. Ra...

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Bibliographic Details
Main Authors: Astrid Vallès, Lindsay Grijpink-Ongering, Freddy M. de Bree, Tinka Tuinstra, Eric Ronken
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Neurobiology of Disease
Subjects:
KC
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105003141