High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming.

Several methods allow reprogramming of differentiated somatic cells to embryonic stem cell-like cells. However, the process of reprogramming remains inefficient and the underlying molecular mechanisms are poorly understood. Here, we report the optimization of somatic cell fusion with embryonic stem...

Full description

Bibliographic Details
Main Authors: Connie C Wong, Alexandre Gaspar-Maia, Miguel Ramalho-Santos, Renee A Reijo Pera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2278370?pdf=render