Cyr61/CCN1 displays high-affinity binding to the somatomedin B(1-44) domain of vitronectin.

Cyr61/CCN1 displays high-affinity binding to the somatomedin B(1-44) domain of vitronectin.

Cyr61 is a member of the CCN (Cyr61, connective tissue growth, NOV) family of extracellular-associated (matricellular) proteins that present four distinct functional modules, namely insulin-like growth factor binding protein (IGFBP), von Willebrand factor type C (vWF), thrombospondin type 1 (TSP), a...

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Bibliographic Details
Main Authors: Ivo M B Francischetti, Michalis Kotsyfakis, John F Andersen, Jan Lukszo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2829074?pdf=render

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