| Summary: | Abstract Background May Thurner syndrome is relatively unknown to physicians, its management is well standardized and the outcomes of treatment are satisfactory in the short to medium term. Case presentation We report the case of a patient who suffered from venous claudication during running which impaired their quality of life, decreased their athletic performance and resulted in a career change. May Thurner syndrome diagnosis was made after extensive hemodynamic analysis of a lower limb venous duplex ultrasound scan. This diagnosis was later confirmed by imaging. Subsequent endovascular care provided rapid and sustained clinical improvement. Conclusion The main difficulties with the May Thurner syndrome are to think about it and know how to look for it; indeed the misdiagnosis time can be long. When diagnosis is made, treatment could be easy and effective.
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