A peephole into the brain: Neuropathological features of Alzheimer’s Disease revealed by in vivo two-photon imaging
Alzheimer’s disease (AD) is a protein conformational disorder characterized by two major neuropathological features: extracellular accumulations of amyloid-beta peptide in the form of plaques and intracellular tangles, consisting of hyperphosphorylated tau proteins. Several morphological and functio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-04-01
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Series: | Frontiers in Psychiatry |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2012.00026/full |