A peephole into the brain: Neuropathological features of Alzheimer’s Disease revealed by in vivo two-photon imaging

Alzheimer’s disease (AD) is a protein conformational disorder characterized by two major neuropathological features: extracellular accumulations of amyloid-beta peptide in the form of plaques and intracellular tangles, consisting of hyperphosphorylated tau proteins. Several morphological and functio...

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Bibliographic Details
Main Authors: Sabine eLiebscher, Melanie eMeyer-Luehmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2012.00026/full