Association between the c. 2495 A>G ATP7B Polymorphism and Sporadic Alzheimer's Disease

Association between the c. 2495 A>G ATP7B Polymorphism and Sporadic Alzheimer's Disease

Nonceruloplasmin-bound copper (“free”) is reported to be elevated in Alzheimer's disease (AD). In Wilson's disease (WD) Cu-ATPase 7B protein tightly controls free copper body levels. To explore whether the ATP7B gene harbours susceptibility loci for AD, we screened 180 AD chromosomes for s...

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Bibliographic Details
Main Authors:	Serena Bucossi, Stefania Mariani, Mariacarla Ventriglia, Renato Polimanti, Massimo Gennarelli, Cristian Bonvicini, Patrizio Pasqualetti, Federica Scrascia, Simone Migliore, Fabrizio Vernieri, Paolo M. Rossini, Rosanna Squitti
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	International Journal of Alzheimer's Disease
Online Access:	http://dx.doi.org/10.4061/2011/973692

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