Intramedullary injury combined with osteoporosis therapeutics regulates targeted local osteogenesis

Intramedullary injury combined with osteoporosis therapeutics regulates targeted local osteogenesis

Abstract Bone marrow ablation prompts transient bone formation in nearly the entire medullary cavity before marrow regeneration occurs. Here, we establish a procedure to direct bone formation in a desired particular site within the medullary cavity for support of biomedical devices. Local intramedul...

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Bibliographic Details
Main Authors: Yoko Miyazaki-Asato, Kiyono Koi, Hiroki Fujimoto, Kae Kakura, Hirofumi Kido, Tsukasa Yanagi, Junro Yamashita
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80316-y

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