Clinical and genetic analysis of recurrent adult-type granulosa cell tumor of the ovary: Persistent preservation of heterozygous c.402C>G FOXL2 mutation.

Clinical and genetic analysis of recurrent adult-type granulosa cell tumor of the ovary: Persistent preservation of heterozygous c.402C>G FOXL2 mutation.

BACKGROUND:Adult-type granulosa cell tumors of the ovary (aGCTs) are rare tumors that represent 2-5% of ovarian malignancies. The prognosis of this tumor is favorable, and it is characterized by slow progression. 10-30% of these tumors recur after 4-7 years of the primary surgery and the 5-year surv...

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Bibliographic Details
Main Authors: Satoshi Yanagida, Michael S Anglesio, Tayyebeh M Nazeran, Amy Lum, Momoko Inoue, Yasushi Iida, Hirokuni Takano, Takashi Nikaido, Aikou Okamoto, David G Huntsman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5464638?pdf=render

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