l-Glutamate Enhances Methylmercury Toxicity by Synergistically Increasing Oxidative Stress

Methylmercury (MeHg) is a well-known environmental toxicant. With its lipophilic nature and high reactivity to sulfhydryl groups, it is widely distributed and accumulated in the body to damage cells. Oxidative stress is proposed as a major mechanism underlying the cytotoxic action of MeHg. In the pr...

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Bibliographic Details
Main Authors: Sirirat Amonpatumrat, Hiroyuki Sakurai, Pattama Wiriyasermkul, Narakorn Khunweeraphong, Shushi Nagamori, Hidekazu Tanaka, Pawinee Piyachaturawat, Yoshikatsu Kanai
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313350