Combined treatment with electrical stimulation and insulin-like growth factor-1 promotes bone regeneration in vitro.

Electrical stimulation (ES) and insulin-like growth factor-1 (IGF-1) are widely used in bone regeneration because of their osteogenic activity. However, the combined effects of ES and supplemental IGF-1 on the whole bone formation process remain unclear. In this study, fluorescence staining and an M...

Full description

Bibliographic Details
Main Authors: Zhiping Qi, Peng Xia, Su Pan, Shuang Zheng, Chuan Fu, Yuxin Chang, Yue Ma, Jincheng Wang, Xiaoyu Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5944947?pdf=render