Design, Synthesis and Biological Evaluation of Novel N-Pyridyl-Hydrazone Derivatives as Potential Monoamine Oxidase (MAO) Inhibitors

Design, Synthesis and Biological Evaluation of Novel N-Pyridyl-Hydrazone Derivatives as Potential Monoamine Oxidase (MAO) Inhibitors

A new series of N-pyridyl-hydrazone derivatives was synthesized by using a simple and efficient method. The final compounds obtained were screened for their inhibitory potency against monoamine oxidase (MAO) A and B. The newly synthesized compounds 2a–2n specifically inhibited monoamine oxidases, di...

Full description

Bibliographic Details
Main Authors: Gülhan Turan-Zitouni, Weiam Hussein, Begüm Nurpelin Sağlık, Aouatef Tabbi, Büşra Korkut
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
MAO inhibitors
N-pyridyl-hydrazone derivatives
inhibitory potency
enzyme kinetic studies
Online Access:http://www.mdpi.com/1420-3049/23/1/113

Similar Items

Similar Items