Membrane assembly of Shiga toxin glycosphingolipid receptors and toxin refractiveness of MDCK II epithelial cells

Membrane assembly of Shiga toxin glycosphingolipid receptors and toxin refractiveness of MDCK II epithelial cells

Shiga toxins (Stxs) are the major virulence factors of Stx-producing Escherichia coli (STEC), which cause hemorrhagic colitis and severe extraintestinal complications due to injury of renal endothelial cells, resulting in kidney failure. Since kidney epithelial cells are suggested additional targets...

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Bibliographic Details
Main Authors: Nadine Legros, Gottfried Pohlentz, Daniel Steil, Ivan U. Kouzel, Ivan Liashkovich, Alexander Mellmann, Helge Karch, Johannes Müthing
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Lipid Research
Subjects:
Forssman glycosphingolipid
globo-series
glycolipids
lysophospholipids
Madin-Darby canine kidney
mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330509

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http://www.sciencedirect.com/science/article/pii/S0022227520330509

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