A phase 1, first-in-human study of 18F-GP1 positron emission tomography for imaging acute arterial thrombosis

A phase 1, first-in-human study of 18F-GP1 positron emission tomography for imaging acute arterial thrombosis

Abstract Background 18F-GP1 is a novel positron emission tomography (PET) tracer that targets glycoprotein IIb/IIIa receptors on activated platelets. The study objective was to explore the feasibility of directly imaging acute arterial thrombosis (AAT) with 18F-GP1 PET/computed tomography (PET/CT) a...

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Main Authors: Sun Young Chae, Tae-Won Kwon, Soyoung Jin, Sun U. Kwon, Changhwan Sung, Seung Jun Oh, Sang Ju Lee, Jungsu S. Oh, Youngjin Han, Yong-Pil Cho, Narae Lee, Ji Young Kim, Norman Koglin, Mathias Berndt, Andrew W. Stephens, Dae Hyuk Moon
Format: Article
Language:English
Published: SpringerOpen 2019-01-01
Series:EJNMMI Research
Subjects:
Arterial thrombosis
Positron emission tomography
18F-GP1
Platelet activation
Glycoprotein IIb/IIIa receptor
Online Access:http://link.springer.com/article/10.1186/s13550-018-0471-8

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