Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos

Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos

In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.

Bibliographic Details
Main Authors: Piergiuseppe Quarato, Meetali Singh, Eric Cornes, Blaise Li, Loan Bourdon, Florian Mueller, Celine Didier, Germano Cecere
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21691-6
Description
Summary:In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.
ISSN:2041-1723

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