Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report

Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report

Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a pat...

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Main Authors: Dietrich Sturm, Tobias Schmidt-Wilcke, Tineke Greiner, Christoph Maier, Marc Schargus, Martin Tegenthoff, Matthias Vorgerd
Format: Article
Language:English
Published: Karger Publishers 2016-06-01
Series:Case Reports in Neurology
Subjects:
Confocal cornea microscopy
Small-fiber neuropathy
Multiple myeloma
Skin biopsy
Amyloid neuropathy
Online Access:http://www.karger.com/Article/FullText/446538
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spelling doaj-809c799cbabc44b0943b592202e851bb2020-11-24T22:56:51ZengKarger PublishersCase Reports in Neurology1662-680X2016-06-018213413910.1159/000446538446538Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case ReportDietrich SturmTobias Schmidt-WilckeTineke GreinerChristoph MaierMarc SchargusMartin TegenthoffMatthias VorgerdChanges in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a patient suffering from neuropathy caused by AL amyloidosis and underlying multiple myeloma. Small-fiber damage was detected by CCM.http://www.karger.com/Article/FullText/446538Confocal cornea microscopySmall-fiber neuropathyMultiple myelomaSkin biopsyAmyloid neuropathy
collection DOAJ
language English
format Article
sources DOAJ
author Dietrich Sturm
Tobias Schmidt-Wilcke
Tineke Greiner
Christoph Maier
Marc Schargus
Martin Tegenthoff
Matthias Vorgerd
spellingShingle Dietrich Sturm
Tobias Schmidt-Wilcke
Tineke Greiner
Christoph Maier
Marc Schargus
Martin Tegenthoff
Matthias Vorgerd
Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
Case Reports in Neurology
Confocal cornea microscopy
Small-fiber neuropathy
Multiple myeloma
Skin biopsy
Amyloid neuropathy
author_facet Dietrich Sturm
Tobias Schmidt-Wilcke
Tineke Greiner
Christoph Maier
Marc Schargus
Martin Tegenthoff
Matthias Vorgerd
author_sort Dietrich Sturm
title Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_short Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_full Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_fullStr Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_full_unstemmed Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_sort confocal cornea microscopy detects involvement of corneal nerve fibers in a patient with light-chain amyloid neuropathy caused by multiple myeloma: a case report
publisher Karger Publishers
series Case Reports in Neurology
issn 1662-680X
publishDate 2016-06-01
description Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a patient suffering from neuropathy caused by AL amyloidosis and underlying multiple myeloma. Small-fiber damage was detected by CCM.
topic Confocal cornea microscopy
Small-fiber neuropathy
Multiple myeloma
Skin biopsy
Amyloid neuropathy
url http://www.karger.com/Article/FullText/446538
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AT tobiasschmidtwilcke confocalcorneamicroscopydetectsinvolvementofcornealnervefibersinapatientwithlightchainamyloidneuropathycausedbymultiplemyelomaacasereport
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