BAG3 Proteomic Signature under Proteostasis Stress

BAG3 Proteomic Signature under Proteostasis Stress

The multifunctional HSP70 co-chaperone BAG3 (BCL-2-associated athanogene 3) represents a key player in the quality control of the cellular proteostasis network. In response to stress<b>, </b>BAG3 specifically targets aggregation-prone proteins to the perinuclear aggresome and promotes th...

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Bibliographic Details
Main Authors: Christof Hiebel, Elisabeth Stürner, Meike Hoffmeister, Georg Tascher, Mario Schwarz, Heike Nagel, Christian Behrends, Christian Münch, Christian Behl
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
BAG3
proteostasis
protein quality control
stress response
autophagy
interactome
Online Access:https://www.mdpi.com/2073-4409/9/11/2416

Internet

https://www.mdpi.com/2073-4409/9/11/2416

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