Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in rabbits: a positive cross talk between bradykinin, nitric oxide and prostaglandin E2
Background: Our previous results showed that nitric oxide (NO) and bradykinin (BK) mediate the arthritis induced by Bothrops jararaca venom (BjV) in rabbits. In this study, we investigated the contribution of each receptor of BK as well as the inter-relationship between NO and eicosanoids in BjV-in...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2002-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629350210306 |
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doaj-807e64843ba24098a41bc8e67a64a0b22020-11-25T00:34:26ZengHindawi LimitedMediators of Inflammation0962-93511466-18612002-01-01111131610.1080/09629350210306Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in rabbits: a positive cross talk between bradykinin, nitric oxide and prostaglandin E2Suzana B. V. Mello0Maria Luiza Guzzo1Luiz Filipe Santiago Lisboa2Sandra H. P. Farsky3Rheumatology Division, Department of Internal Medicine, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, São Paulo, SP 0124–6903, BrazilRheumatology Division, Department of Internal Medicine, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, São Paulo, SP 0124–6903, BrazilRheumatology Division, Department of Internal Medicine, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, São Paulo, SP 0124–6903, BrazilLaboratory of Imunochemistry, Instituto Butantan, Av. Vital Brazil 1500, São Paulo, SP 05503–900, BrazilBackground: Our previous results showed that nitric oxide (NO) and bradykinin (BK) mediate the arthritis induced by Bothrops jararaca venom (BjV) in rabbits. In this study, we investigated the contribution of each receptor of BK as well as the inter-relationship between NO and eicosanoids in BjV-induced arthritis.http://dx.doi.org/10.1080/09629350210306 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Suzana B. V. Mello Maria Luiza Guzzo Luiz Filipe Santiago Lisboa Sandra H. P. Farsky |
| spellingShingle |
Suzana B. V. Mello Maria Luiza Guzzo Luiz Filipe Santiago Lisboa Sandra H. P. Farsky Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in rabbits: a positive cross talk between bradykinin, nitric oxide and prostaglandin E2 Mediators of Inflammation |
| author_facet |
Suzana B. V. Mello Maria Luiza Guzzo Luiz Filipe Santiago Lisboa Sandra H. P. Farsky |
| author_sort |
Suzana B. V. Mello |
| title |
Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in
rabbits: a positive cross talk between bradykinin,
nitric oxide and prostaglandin E2 |
| title_short |
Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in
rabbits: a positive cross talk between bradykinin,
nitric oxide and prostaglandin E2 |
| title_full |
Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in
rabbits: a positive cross talk between bradykinin,
nitric oxide and prostaglandin E2 |
| title_fullStr |
Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in
rabbits: a positive cross talk between bradykinin,
nitric oxide and prostaglandin E2 |
| title_full_unstemmed |
Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in
rabbits: a positive cross talk between bradykinin,
nitric oxide and prostaglandin E2 |
| title_sort |
pharmacological characterisation of arthritis induced by bothrops jararaca venom in
rabbits: a positive cross talk between bradykinin,
nitric oxide and prostaglandin e2 |
| publisher |
Hindawi Limited |
| series |
Mediators of Inflammation |
| issn |
0962-9351 1466-1861 |
| publishDate |
2002-01-01 |
| description |
Background: Our previous results showed that nitric oxide (NO) and bradykinin (BK) mediate the arthritis induced by
Bothrops jararaca venom (BjV) in rabbits. In this study, we investigated the contribution of each receptor of BK as well as the inter-relationship between NO and eicosanoids in BjV-induced arthritis. |
| url |
http://dx.doi.org/10.1080/09629350210306 |
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