Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis

Abstract There is limited evidence supporting the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS. We conducted a retrospective analysis of 10 benign sPJS patients. A forward-vi...

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Main Authors: Akihiko Kida, Yukihiro Shirota, Taro Kawane, Hitoshi Omura, Tatsuo Kumai, Masaaki Yano, Fumitaka Arihara, Yuji Hodo, Koichiro Matsuda, Kohei Ogawa, Mitsuru Matsuda, Akito Sakai, Mitsuhiro Terada, Tokio Wakabayashi
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84024-z
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spelling doaj-807b0697ce584056b98b0be0bc6367282021-03-11T12:21:00ZengNature Publishing GroupScientific Reports2045-23222021-02-011111810.1038/s41598-021-84024-zLong-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosisAkihiko Kida0Yukihiro Shirota1Taro Kawane2Hitoshi Omura3Tatsuo Kumai4Masaaki Yano5Fumitaka Arihara6Yuji Hodo7Koichiro Matsuda8Kohei Ogawa9Mitsuru Matsuda10Akito Sakai11Mitsuhiro Terada12Tokio Wakabayashi13Department of Gastroenterology, JA Toyama Kouseiren Takaoka HospitalDepartment of Gastroenterology, Saiseikai Kanazawa HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Gastroenterology, Saiseikai Kanazawa HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Gastroenterology, Saiseikai Kanazawa HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Internal Medicine, Toyama Prefectural Central HospitalDepartment of Gastroenterology, JA Toyama Kouseiren Takaoka HospitalDepartment of Gastroenterology, Saiseikai Kanazawa HospitalAbstract There is limited evidence supporting the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS. We conducted a retrospective analysis of 10 benign sPJS patients. A forward-viewing endoscope was used in all sessions. Following items were evaluated: technical success, adverse events, and clinical outcome of ERPD. The technical success rate was 100% (10/10) in initial ERPD; 9 patients had a pancreatic stent (no-internal-flap: n = 4, internal-flap: n = 5). The median follow-up was 920 days. Four patients developed recurrence. Among them, 3 had a stent with no-internal-flap in initial ERPD, the stent migrated in 3 at recurrence, and a stent was not placed in 1 patient in initial ERPD. Four follow-up interventions were performed. No recurrence was observed in 6 patients. None of the stents migrated (no-internal-flap: n = 1, internal-flap: n = 5) and no stents were replaced due to stent failure. Stenting with no-internal-flap was associated with recurrence (p = 0.042). Mild adverse events developed in 14.3% (2/14). In conclusions, ERPD was performed safely with high technical success. Recurrence was common after stenting with no-internal-flap. Long-term stenting did not result in stent failure. Clinical trial register and their clinical registration number: Nos. 58-115 and R2-9.https://doi.org/10.1038/s41598-021-84024-z
collection DOAJ
language English
format Article
sources DOAJ
author Akihiko Kida
Yukihiro Shirota
Taro Kawane
Hitoshi Omura
Tatsuo Kumai
Masaaki Yano
Fumitaka Arihara
Yuji Hodo
Koichiro Matsuda
Kohei Ogawa
Mitsuru Matsuda
Akito Sakai
Mitsuhiro Terada
Tokio Wakabayashi
spellingShingle Akihiko Kida
Yukihiro Shirota
Taro Kawane
Hitoshi Omura
Tatsuo Kumai
Masaaki Yano
Fumitaka Arihara
Yuji Hodo
Koichiro Matsuda
Kohei Ogawa
Mitsuru Matsuda
Akito Sakai
Mitsuhiro Terada
Tokio Wakabayashi
Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
Scientific Reports
author_facet Akihiko Kida
Yukihiro Shirota
Taro Kawane
Hitoshi Omura
Tatsuo Kumai
Masaaki Yano
Fumitaka Arihara
Yuji Hodo
Koichiro Matsuda
Kohei Ogawa
Mitsuru Matsuda
Akito Sakai
Mitsuhiro Terada
Tokio Wakabayashi
author_sort Akihiko Kida
title Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_short Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_full Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_fullStr Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_full_unstemmed Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_sort long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-02-01
description Abstract There is limited evidence supporting the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS. We conducted a retrospective analysis of 10 benign sPJS patients. A forward-viewing endoscope was used in all sessions. Following items were evaluated: technical success, adverse events, and clinical outcome of ERPD. The technical success rate was 100% (10/10) in initial ERPD; 9 patients had a pancreatic stent (no-internal-flap: n = 4, internal-flap: n = 5). The median follow-up was 920 days. Four patients developed recurrence. Among them, 3 had a stent with no-internal-flap in initial ERPD, the stent migrated in 3 at recurrence, and a stent was not placed in 1 patient in initial ERPD. Four follow-up interventions were performed. No recurrence was observed in 6 patients. None of the stents migrated (no-internal-flap: n = 1, internal-flap: n = 5) and no stents were replaced due to stent failure. Stenting with no-internal-flap was associated with recurrence (p = 0.042). Mild adverse events developed in 14.3% (2/14). In conclusions, ERPD was performed safely with high technical success. Recurrence was common after stenting with no-internal-flap. Long-term stenting did not result in stent failure. Clinical trial register and their clinical registration number: Nos. 58-115 and R2-9.
url https://doi.org/10.1038/s41598-021-84024-z
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