The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells

The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells

Abstract Background Millions of people are affected with retinal diseases that eventually cause blindness, and retinal progenitor cell (RPC) transplantation is a promising therapeutic avenue. However, RPC expansion and the underlying regulation mechanisms remain elusive. Methods Adult mouse neural R...

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Bibliographic Details
Main Authors: Caixia Jin, Qingjian Ou, Zongyi Li, Juan Wang, Jieping Zhang, Haibin Tian, Jing-Ying Xu, Furong Gao, Lixia Lu, Guo-Tong Xu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Stem Cell Research & Therapy
Subjects:
Retina
Progenitor cells
Wnt pathway
Cellular therapy
Transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-018-1091-y

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