TNFα increases tyrosine hydroxylase expression in human monocytes

TNFα increases tyrosine hydroxylase expression in human monocytes

Abstract Most, if not all, peripheral immune cells in humans and animals express tyrosine hydroxylase (TH), the rate limiting enzyme in catecholamine synthesis. Since TH is typically studied in the context of brain catecholamine signaling, little is known about changes in TH production and function...

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Bibliographic Details
Main Authors: Adithya Gopinath, Martin Badov, Madison Francis, Gerry Shaw, Anthony Collins, Douglas R. Miller, Carissa A. Hansen, Phillip Mackie, Malú Gámez Tansey, Abeer Dagra, Irina Madorsky, Adolfo Ramirez-Zamora, Michael S. Okun, Wolfgang J. Streit, Habibeh Khoshbouei
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00201-x

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