CLINICAL AND IMMUNOLOGIC IMPORTANCE OF MDR1/PGP 170 EXPRESSION IN PATIENTS WITH BREAST CANCER

Clinical, morphologic and immunohistochemical data of 51 patients with stage T2N1-3M0 breast cancer treated in the N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences in 2002 was analyzed. Expression of Pgp 170 was found in 19 patients. Relationship between immunopheno...

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Bibliographic Details
Main Authors: D. A. Yengay, I. V. Poddubnaya, N. N. Tupitsin, Ye. B. Mechetner
Format: Article
Language:Russian
Published: ABV-press 2014-09-01
Series:Opuholi Ženskoj Reproduktivnoj Sistemy
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/362
Description
Summary:Clinical, morphologic and immunohistochemical data of 51 patients with stage T2N1-3M0 breast cancer treated in the N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences in 2002 was analyzed. Expression of Pgp 170 was found in 19 patients. Relationship between immunophenotype of stage T2N1-3M0 breast cancer cells and main clinical and morphologic fea- tures, treatment provided and expression of multiple drug resistance gene MDR1.
ISSN:1994-4098
1999-8627