Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning

Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning

Abstract Background Cancer cachexia is a progressive and multi-factorial metabolic syndrome characterized by loss of adipose tissue and skeletal muscle. White adipose tissue (WAT) lipolysis and white-to-brown transdifferentiation of WAT (WAT browning) are proposed to contribute to WAT atrophy in can...

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Bibliographic Details
Main Authors: Jun Han, Qingyang Meng, Lei Shen, Guohao Wu
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Lipids in Health and Disease
Subjects:
Interleukin-6
Cancer cachexia
Lipolysis
Beige adipocyte
Online Access:http://link.springer.com/article/10.1186/s12944-018-0657-0

Internet

http://link.springer.com/article/10.1186/s12944-018-0657-0

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