The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery

The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery

Summary: Signal transduction pathways stimulated by secreted growth factors are tightly regulated at multiple levels between the cell surface and the nucleus. The trafficking of cell surface receptors is emerging as a key step for regulating appropriate cellular responses, with perturbations in this...

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Bibliographic Details
Main Authors: Daniel S.J. Miller, Robert D. Bloxham, Ming Jiang, Ilaria Gori, Rebecca E. Saunders, Debipriya Das, Probir Chakravarty, Michael Howell, Caroline S. Hill
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718316450

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http://www.sciencedirect.com/science/article/pii/S2211124718316450

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