AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injury.

AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injury.

AIMS: Ischemic preconditioning (IPC) is a potent form of endogenous protection. However, IPC-induced cardioprotective effect is significantly blunted in insulin resistance-related diseases and the underlying mechanism is unclear. This study aimed to determine the role of glucose metabolism in IPC-re...

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Bibliographic Details
Main Authors: Lele Ji, Xing Zhang, Wenchong Liu, Qichao Huang, Weidong Yang, Feng Fu, Heng Ma, Hui Su, Haichang Wang, Jing Wang, Haifeng Zhang, Feng Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724784?pdf=render

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