First Metal-Free Synthesis of Tetracyclic Pyrido and Pyrazino Thienopyrimidinone Molecules

First Metal-Free Synthesis of Tetracyclic Pyrido and Pyrazino Thienopyrimidinone Molecules

We report herein a new metal free synthetic pathway to generate tetracyclic compounds from 3-aminothieno[3,2-b]pyridine-2-carboxylate. To enlarge the molecular diversity, we studied the Suzuki coupling of 9-chloro-6H-pyrido[1,2-a]pyrido[2′,3′:4,5]thieno[3,2-d]pyrimidin-6-one and several boronic acid...

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Bibliographic Details
Main Authors: Mohammed Aounzou, Joana F. Campos, Mohammed Loubidi, Sabine Berteina-Raboin
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
metal-free
thienopyrimidinone
tetracyclic compounds
Online Access:http://www.mdpi.com/1420-3049/23/5/1159

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