Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding

Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding

<p>Abstract</p> <p>Background</p> <p>Aggregation of the amyloid peptides, Aβ40 and Aβ42, is known to be involved in the pathology of Alzheimer's disease (AD). Here we investigate the relationship between peptide aggregation and cell surface binding of three forms o...

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Bibliographic Details
Main Authors: McLaurin JoAnne, Bateman David A, Chakrabartty Avijit
Format: Article
Language:English
Published: BMC 2007-05-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/29

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