ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-03-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-03326-5 |