CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean...
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Scientific Сentre for Family Health and Human Reproduction Problems
2012-05-01
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| Series: | Acta Biomedica Scientifica |
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| Online Access: | https://www.actabiomedica.ru/jour/article/view/850 |
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doaj-8003ca5177bd4b2399d9bf5c9b6fb77d2021-08-17T13:52:38ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-05-0103(1)3640796CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESISA. V. Labygina0L. M. Lazareva1L. V. Suturina2L. I. Kolesnikova3L. F. Sholokhov4E. E. Khramova5T. L. Olifirenko6E. S. Shaulskaya7Russian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionRussian Academy of Medical Sciences Siberian Branch Establishment of RAMS Scientific Centre of the Problems of Family Health and Human ReproductionThe article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean age 14,6 ± 3,4 years). The control group included 35 healthy adolescent girls (mean age 15,8 ± 0,89 years). Hyperprolactinemia (tumor and non-neoplastic) in puberty leads to disorders of sexual development and ovarian-menstrual cycle, followed by neurological symptoms. Elevated concentrations of testosterone, cortisol, DHEA, 17-OH-progesterone and LH/FSH ratio were shown in adolescents with hyperprolactinemia compared to the control group. Macroprolactinemia was estimated in 16,4—20 % of girls with hyperprolactinemia.https://www.actabiomedica.ru/jour/article/view/850hyperprolactinemiamacroprolactinemiaimpaired of sexual developmentmenstrual cycle garueniehyperandrogenismanovulation |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
A. V. Labygina L. M. Lazareva L. V. Suturina L. I. Kolesnikova L. F. Sholokhov E. E. Khramova T. L. Olifirenko E. S. Shaulskaya |
| spellingShingle |
A. V. Labygina L. M. Lazareva L. V. Suturina L. I. Kolesnikova L. F. Sholokhov E. E. Khramova T. L. Olifirenko E. S. Shaulskaya CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS Acta Biomedica Scientifica hyperprolactinemia macroprolactinemia impaired of sexual development menstrual cycle garuenie hyperandrogenism anovulation |
| author_facet |
A. V. Labygina L. M. Lazareva L. V. Suturina L. I. Kolesnikova L. F. Sholokhov E. E. Khramova T. L. Olifirenko E. S. Shaulskaya |
| author_sort |
A. V. Labygina |
| title |
CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS |
| title_short |
CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS |
| title_full |
CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS |
| title_fullStr |
CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS |
| title_full_unstemmed |
CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS |
| title_sort |
characteristics of pituitary-opvarian-adrenal axis in adolescent girls with hyperprolactinemia of various genesis |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| series |
Acta Biomedica Scientifica |
| issn |
2541-9420 2587-9596 |
| publishDate |
2012-05-01 |
| description |
The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean age 14,6 ± 3,4 years). The control group included 35 healthy adolescent girls (mean age 15,8 ± 0,89 years). Hyperprolactinemia (tumor and non-neoplastic) in puberty leads to disorders of sexual development and ovarian-menstrual cycle, followed by neurological symptoms. Elevated concentrations of testosterone, cortisol, DHEA, 17-OH-progesterone and LH/FSH ratio were shown in adolescents with hyperprolactinemia compared to the control group. Macroprolactinemia was estimated in 16,4—20 % of girls with hyperprolactinemia. |
| topic |
hyperprolactinemia macroprolactinemia impaired of sexual development menstrual cycle garuenie hyperandrogenism anovulation |
| url |
https://www.actabiomedica.ru/jour/article/view/850 |
| work_keys_str_mv |
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