Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies

Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies

<p>Abstract</p> <p>Background</p> <p>Proper expression and functioning of transcription factors (TFs) are essential for regulation of different traits and thus could be crucial for the development of complex diseases. Subjects with Down syndrome (DS) have a higher incid...

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Bibliographic Details
Main Authors: Chatterjee Arpita, Dutta Samikshan, Mukherjee Sanjit, Mukherjee Nupur, Dutta Avirup, Mukherjee Ashis, Sinha Swagata, Panda Chinmay Kumar, Chaudhuri Keya, Roy Ananda L, Mukhopadhyay Kanchan
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Medical Genetics
Subjects:
SIM2
ETS2
Down syndrome
Breast cancer
Oral cancer
Acute lymphoblastic leukemia
Online Access:http://www.biomedcentral.com/1471-2350/14/12

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