Periodic accumulation of regulatory T cells in the uterus: preparation for the implantation of a semi-allogeneic fetus?

BACKGROUND:Naturally occurring Foxp3(+)regulatory T cells play an important role in the inhibition of an immunological attack of the fetus. As implantation of the fetus poses an immediate antigenic challenge, the immune system has to prepare itself for this event prior to implantation. METHODOLOGY A...

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Bibliographic Details
Main Authors: Marinos Kallikourdis, Alexander G Betz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1847704?pdf=render