Quantitative proteomic profiling identifies DPYSL3 as pancreatic ductal adenocarcinoma-associated molecule that regulates cell adhesion and migration by stabilization of focal adhesion complex.

Elucidation of how pancreatic cancer cells give rise to distant metastasis is urgently needed in order to provide not only a better understanding of the underlying molecular mechanisms, but also to identify novel targets for greatly improved molecular diagnosis and therapeutic intervention. We emplo...

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Bibliographic Details
Main Authors: Takeo Kawahara, Naoe Hotta, Yukiko Ozawa, Seiichi Kato, Keiko Kano, Yukihiro Yokoyama, Masato Nagino, Takashi Takahashi, Kiyoshi Yanagisawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855176?pdf=render