INFLAMMATION AND MALE INFERTILITY. WHAT’S IS COMMON?

• Main Author: N G Kulchenko
• Format: Article
• Language: English
• Published: Peoples’ Friendship University of Russia (RUDN University) 2017-12-01
• Series: RUDN Journal of Medicine
• Subjects: активность лейкоцитов; идиопатическое необструктивное мужское бес-плодие; оксидативный стресс
• Online Access: http://journals.rudn.ru/medicine/article/view/17676

All researchers identify the idiopathic forms of male infertility, which can hardly be cor-rected. Objectives: toidentify additional links to pathogenesis of idiopathic male infertility. Materials and methods of research: were examined 24 (54,5%) men with idiopathic non obstructive azoospermia. The comparison group was formed by 20 (45,5%) healthy male volunteers. In order to identify additional links of pathospermia pathogenesis, was determined the leucocytes activity in peripheral blood of patients. Results: in patients with pathospermia reliably more total number of WBC and higher production speed of reactive oxygen species by leukocytes for the selected time interval, in comparison with healthy men (p < 0,05). Conclusion: one of the reasons of non-obstructive azoospermia is chronic inflammations, which induce oxidative stress.