IL1B induced Smad 7 negatively regulates gastrin expression.

BACKGROUND: Helicobacter pylori elicited IL1B is one of the various modulators responsible for perturbation of acid secretion in gut. We have earlier reported that IL1B activated NFkB downregulates gastrin, a major modulator of acid secretion. However, we hypothesized that regulation of gastrin by I...

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Bibliographic Details
Main Authors: Dipanjana Datta De, Sumana Bhattacharjya, Meenakshi Maitra, Arindam Datta, Abhijit Choudhury, G K Dhali, Susanta Roychoudhury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3062540?pdf=render