Medical information system based web technologies for the diagnosis of acute lymphoblastic leukemia and minimal residual disease

• Main Authors: Valentina V. Dmitrieva, Nikolai N. Tupitsyn, Evgeniy V. Polyakov, Elena M. Nosova, Alexandera D. Palladin, Vyacheslav I. Tsyplyak, Kirill A. Liberis
• Format: Article
• Language: English
• Published: Moscow Engineering Physics Institute 2021-09-01
• Series: Bezopasnostʹ Informacionnyh Tehnologij
• Subjects: medical information system, web application, diagnosis of acute leukemia, classification of bone marrow and blood cells, minimal residual disease.
• Online Access: https://bit.mephi.ru/index.php/bit/article/view/1361

The paper considers the implementation of a medical information system (MIS) prototype for the diagnosis of acute leukemia (OL) and minimal residual disease (MRD). The main goal is the integration of intelli-gent computer microscopy and laser flow cytofluorimetry systems – an integrated method for the diagnosis of hemoblastosis using artificial intelligence technologies. The proposed information website provides re-mote access to thematic content for the diagnosis of acute lymphoblastic leukemia (ALL) and the control of minimal residual disease through a specialized cross-platform web application that simulates the opera-tion of various subsystems during research. One of the problems in the development of MIS is to ensure information security both in relation to personal data about the health of patients and the course of the medical and diagnostic process, and information that characterizes the implemented MIS functionality: computer and network equipment, software modules and databases. A special feature of medical infor-mation is its confidentiality. Data security is ensured by user authentication. Protection of information resources from unauthorized access is provided by separation and verification of access privileges for the administrator, doctors and patients. The level of security against external threats is provided via the admin-istration of the web server.