Gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway

Gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway

Gambogic acid (GA) has been shown to inhibit cancer cell proliferation, induce apoptosis, and enhance reactive oxygen species accumulation. However, whether GA could improve multidrug resistance through modulating autophagy has never been explored. We demonstrated that the combination of GA and cisp...

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Bibliographic Details
Main Authors: Teng Zhao, Hong-Jian Wang, Wen-Wen Zhao, Yi-Ling Sun, Li-Kuan Hu
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Gambogic acid
Autophagy
Multidrug resistance
Cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X17301493

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