Evaluation of 111In-Labeled Cyclic RGD Peptides: Effects of Peptide and Linker Multiplicity on Their Tumor Uptake, Excretion Kinetics and Metabolic Stability

Evaluation of 111In-Labeled Cyclic RGD Peptides: Effects of Peptide and Linker Multiplicity on Their Tumor Uptake, Excretion Kinetics and Metabolic Stability

<p><b>Purpose: </b>The purpose of this study was to demonstrate the valence of cyclic RGD peptides, P-RGD (PEG<sub>4</sub>-c(RGDfK): PEG<sub>4</sub> = 15-amino-4,710,13-tetraoxapentadecanoic acid), P-RGD<sub>2</sub> (PEG<sub>4</sub>-E...

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Bibliographic Details
Main Author: Jiyun Shi, Yang Zhou, Sudipta Chakraborty, Young-Seung Kim, Bing Jia, Fan Wang, Shuang Liu
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:Theranostics
Online Access:http://www.thno.org/v01p0322.htm

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