Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na+-HCO3- cotransporter NBCe1

The electrogenic Na+-HCO3- cotransporter NBCe1 plays an essential role in bicarbonate absorption from renal proximal tubules, but also mediates the other biological processes in extrarenal tissues such as bicarbonate secretion from pancreatic ducts, maintenance of tissue homeostasis in eye, enamel m...

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Bibliographic Details
Main Authors: George eSeki, Shoko eHorita, Masashi eSuzuki, Osamu eYamazaki, Tomohiko eUsui, Motonobu eNakamura, Hideomi eYamada
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00270/full