Data set of competitive and allosteric protein kinase inhibitors confirmed by X-ray crystallography
A data set was generated comprising currently available competitive and allosteric human protein kinase inhibitors confirmed by X-ray crystallography. This data set has been used to systematically explore structural relationships between these types of inhibitors with different mechanisms of action....
Main Authors: | Huabin Hu, Oliver Laufkötter, Filip Miljković, Jürgen Bajorath |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
|
Series: | Data in Brief |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340921001001 |
Similar Items
-
Kinase inhibitor data set for systematic analysis of representative kinases across the human kinome
by: Oliver Laufkötter, et al.
Published: (2020-10-01) -
Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico
by: Jakob Fleischmann, et al.
Published: (2021-03-01) -
Recent Advances in the Discovery of CK2 Allosteric Inhibitors: From Traditional Screening to Structure-Based Design
by: Xiaolan Chen, et al.
Published: (2020-02-01) -
Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey
by: Gaëlle Mariaule, et al.
Published: (2014-09-01) -
HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors
by: Pratibha C Koneru, et al.
Published: (2019-05-01)