Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology

Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology

Abstract Colostrum quality is a vital factor in mortality and growth performance for piglets. Lactoferrin is an immuno-active milk protein that contributes to the formation of a protective layer above intestinal mucosa, possesses the antibacterial and antiviral activities that are favorable for pigl...

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Bibliographic Details
Main Authors: Xiaosong Han, Yang Gao, Guanglei Li, Youcai Xiong, Changzhi Zhao, Jinxue Ruan, Yunlong Ma, Xinyun Li, Changchun Li, Shuhong Zhao, Shengsong Xie
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cell & Bioscience
Subjects:
Pig
Lactoferrin
Colostrum
CRISPR/Cas9
Homologous recombination
Online Access:http://link.springer.com/article/10.1186/s13578-020-00496-y

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