Choline kinase inhibitors synergize with TRAIL in the treatment of colorectal tumors and overcomes TRAIL resistance

Choline kinase inhibitors synergize with TRAIL in the treatment of colorectal tumors and overcomes TRAIL resistance

Aim: The aim of this study was to investigate the effects of the combination of choline kinase inhibitor MN58b and tumor necrosis factor-related apoptosis inducing ligand (TRAIL) against colon cancer cells. Methods: TRAIL-sensitive (DLD-1) and TRAIL-resistant (SW620) cells were treated with MN58b an...

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Bibliographic Details
Main Authors:	Juan Carlos Lacal, Ladislav Andera
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2016-01-01
Series:	Cancer Translational Medicine
Subjects:	Choline kinase inhibitors colon cancer combinatorial chemotherapy DR5 tumor necrosis factor-related apoptosis inducing ligand tumor necrosis factor-related apoptosis inducing ligand resistance
Online Access:	http://www.cancertm.com/article.asp?issn=2395-3977;year=2016;volume=2;issue=6;spage=163;epage=174;aulast=Lacal

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