Disclosing the Potential of the SARP-Type Regulator PapR2 for the Activation of Antibiotic Gene Clusters in Streptomycetes

Disclosing the Potential of the SARP-Type Regulator PapR2 for the Activation of Antibiotic Gene Clusters in Streptomycetes

Streptomyces antibiotic regulatory protein (SARP) family regulators are well-known activators of antibiotic biosynthesis in streptomycetes. The respective genes occur in various types of antibiotic gene clusters encoding, e.g., for polyketides, ribosomally and non-ribosomally synthesized peptides, o...

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Bibliographic Details
Main Authors: Janina Krause, Ira Handayani, Kai Blin, Andreas Kulik, Yvonne Mast
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Microbiology
Subjects:
actinomycetes
Streptomyces
antibiotic
regulator
SARP
silent gene cluster
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00225/full

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