Increased infiltration and tolerised antigen-specific CD8+ TEM cells in tumor but not peripheral blood have no impact on survival of HCMV+ glioblastoma patients

Increased infiltration and tolerised antigen-specific CD8+ TEM cells in tumor but not peripheral blood have no impact on survival of HCMV+ glioblastoma patients

Human cytomegalovirus (HCMV) antigens in glioblastoma (GBM) present opportunities for personalised immunotherapy. However, their presence in GBM tissue is still under debate, and evidence of their impact on functional immune responses and prognosis is sparse. Here, we investigated the presence of pp...

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Bibliographic Details
Main Authors: M. Bahador, A. Gras Navarro, M.A. Rahman, M. Dominguez-Valentin, S. Sarowar, E. Ulvestad, G. Njølstad, S.A. Lie, E.K. Kristoffersen, E. Bratland, M. Chekenya
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:OncoImmunology
Subjects:
hcmv
glioblastoma
hla-restricted t-cells
memory t-cells
survival
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1336272

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